Zitat:
"The most striking finding of Talic and colleagues’ systematic review is that only one completed randomised trial of a public health and social measures (PHSM) was identified, in contrast with the hundreds for trials completed for drug treatments of covid-19."
Eine Bewertung der Wirksamkeit von Quarantäne, Lockdowns, Grenz- oder Schulschließungen, sowie Home-Office war nicht möglich. In Summe wird der erwünschte Effekt vieler nicht-medikamentöser Maßnahmen überschätzt.
Zitat:
"What can we take from this new review? It might be reasonable to conclude that a bundle of PHSMs is modestly effective but that individual components cannot be reliability assessed owing to lack of adjustment for confounders or use of randomised or factorial trials. Face masks seem to have a real but small effect for wearer and source control, although final conclusions should await full reports of the trials from Bangladesh and Guinea-Bissau. However, the quality of the current evidence would be graded - by GRADE criteria - as low or very low, as it consists of mainly observational studies with poor methods (biases in measurement of outcomes, classification of PHSM, and missing data), and high heterogeneity of effect size. More and better research are needed.
