Zitat:
This population-based study used the French National Health Data System linked to the national COVID-19 vaccination database. Eligible participants were all persons unvaccinated or vaccinated with the BNT162b2 vaccine, aged 75 years or older, admitted to the hospital between December 15, 2020, and April 30, 2021, for acute myocardial infarction, hemorrhagic stroke, ischemic stroke, or pulmonary embolism (diagnoses identified using the International Statistical Classification of Diseases and Related Health Problems, Tenth Revision codes) (Table 1 and eTable in the Supplement).
We undertook within-person comparisons using a self-controlled case-series method adapted to cardiovascular event–dependent exposures and high event-related mortality that can cancel or defer subsequent vaccination or increase short-term mortality2 (eMethods in the Supplement). Only exposures preceding the event were considered. Exposure risk intervals were days 1 through 14 following each of the 2 vaccine doses. The exposure risk interval was further subdivided into days 1 through 7 and days 8 through 14. Except for the vaccination day, the remaining periods were regarded as nonrisk periods.
Die Gesamtlaufzeit waren also 4 Monate und 15 Tage maximal.