Hi,
Die Variante B.1.1.7, die sich schneller verbreitet, ist irgendwie doch nicht gefährlicher als andere Varianten:
Zitat:
British variant of COVID-19 not as severe as feared - The Lancet
Zitat:
The researchers found no difference in risks of severe disease, death, or other clinical outcomes in patients with B.1.1.7 and other variants.
https://www.reuters.com/article/us-h...-idUSKBN2BZ2SS
Link zur Original-Studie:
https://www.thelancet.com/journals/l...170-5/fulltext
Das hier ist auch interessant:
Zitat:
Autoimmune disease treatments may reduce vaccine responses
Zitat:
Most patients in the study "were able to mount antibody responses in response to SARS-CoV-2 vaccination, which is reassuring," said coauthor Alfred Kim from Washington University School of Medicine in St. Louis. It is not clear yet whether reduced antibody levels will result in decreased protection from infection or hospitalization, Kim said. Particularly concerning, he said, is the 10-fold reduction in vaccine-induced antibody levels seen in patients who routinely use steroids such as prednisone and methylprednisolone and a 36-fold reduction seen with drugs that deplete B cells, including Roche's Rituxan (rituximab) and Ocrevus (ocrelizumab).
Wurde das nicht immer als Argument FÜR die Impfungen gegenüber der natürlichen Immunantwort genommen, da hier zu wenig Antikörper nachweisbar sind und jetzt ist es doch nicht sicher, dass es ein verringerten Schutz bedeutet?:gruebel:
Die Mutationen bei der Arbeit:
Zitat:
Most antibody drugs ineffective against Brazil variant
Zitat:
The coronavirus variant first identified in Brazil, known as P.1, is resistant to three of the four antibody therapies with emergency use authorization in the United States, according to a laboratory study.
Den Part hier verstehe ich nicht so ganz:
Zitat:
The researchers also exposed P.1 to plasma from COVID-19 survivors and blood from recipients of vaccines from Pfizer/BioNTech or Moderna. Compared to their effects against the original version of the coronavirus, the plasma and the vaccine-induced antibodies were less effective at neutralizing P.1. In earlier studies, however, they were even less effective against the B.1.351 variant first identified in South Africa. This suggests that the Brazil variant might not pose as great a threat of reinfection or decreased vaccine protection as the South Africa variant, said coauthor David Ho from Columbia University. Real-world evidence is needed to confirm the lab results, he said. (bit.ly/2Qgv4j1)
Es ist also weniger effektiv gegen P.1., aber das wurde schon bei der Süd Afrika Variante gesagt, weshalb sie wohl keine große Gefahr darstellt für Reinfektionen und dem Impfschutz!:weirdface
Haben die sich da irgendwie unglücklich ausgedrückt, oder kann mir einer diese erklären?:gruebel:
Zitat:
South Africa variant can ‘break through’ Pfizer vaccine
Zitat:
The B.1.351 coronavirus variant discovered in South Africa can "break through" Pfizer/BioNTech's COVID-19 vaccine protection to some extent, Israeli researchers have found. They compared almost 400 people who had tested positive for COVID-19 after one or two doses of the vaccine, against the same number of similar people with COVID-19 who were unvaccinated. The prevalence of the variant in Israel is low, and overall, it accounted for about 1% of all the COVID-19 cases in the study. But among those who received both doses of the vaccine, a larger proportion of COVID-19 infections were caused by B.1.351. The "disproportionately higher rate" of the South African variant in the fully vaccinated group (5.4%) compared to the rate in the unvaccinated group (0.7%) "means that the South African variant is able, to some extent, to break through the vaccine's protection," said Tel Aviv University's Adi Stern. In a report posted on Friday on medRxiv ahead of peer review, Stern's team said the research was not intended to deduce overall vaccine effectiveness against any variant, since it only looked at people who had already tested positive for COVID-19, not at overall infection rates in the community. (bit.ly/3sdVzCR; reut.rs/32aqvt0)
Immunität gegen A, also macht sich Variante B breit!
Wobei ich es interessant finde, dass B.1.351 bei den Ungeimpften so wenig nachgewiesen wurde, eigentlich müssten diese doch genauso davon betroffen sein, oder?:gruebel: (Vielleicht spielt das Verhalten der Geimpften mit rein?)
https://www.reuters.com/article/us-h...-idUSKBN2BZ2H1
Gruß
Alef
